You can use line crimp sleeves instead of a knot... I recommend you save it for leader line, I wouldn't spool a reel with it and use it for big butts. Nylon has to much stretch, and the large diameter of 80lb. test will create drag in the water causing your line to angle to far back fishing in deep water with a current. Better off using non stretch thin braid line or one of the many brands out there, Tuff Line,Spider wire ect. ect. What type of reel are you planning on putting this line on? 80lb. will take up lots of spool space, reducing your line yardage on the reel. If you have a big enough reel I'm sure it would work.. .. use crimp sleeves or test a variety of knots until you find one that will work with your 80lb. mono..