All Things COVID-19

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Foxsea said:
Sadly, as they say "Can't fix stupid."
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Sadly - you are right, Foxsea - we can't "FIX" stupid - but maybe we can lighten their pocketbook and give them something to consider the next time they want to risk a child in their foolishness, maybe?
 
GLG said:
U of A virology lab finds drug originally meant for Ebola is effective against a key enzyme of coronavirus that causes COVID-19

Remdesivir already in human trials in search for treatment of deadly disease.

Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published today in the Journal of Biological Chemistry.

The paper follows closely on research published by the same lab in late February that demonstrated how the drug worked against the Middle East Respiratory Syndrome (MERS) virus, a related coronavirus.

More here
https://www.folio.ca/u-of-a-virolog...y-enzyme-of-coronavirus-that-causes-covid-19/

“We were optimistic that we would see the same results against the SARS-CoV-2 virus,” said Matthias Götte, chair of medical microbiology and immunology at U of A.

“We obtained almost identical results as we reported previously with MERS, so we see that remdesivir is a very potent inhibitor for coronavirus polymerases.”
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My pharmacist friends tell me you cannot be sure a drug is doing what is claimed until proper double blind clinical trials have been done repeatedly by peer evaluation. Simply said: "prove it".
Prof Stephen Evans, Professor of Pharmacoepidemiology, London School of Hygiene & Tropical Medicine, said:
“The data from this paper are almost uninterpretable. It is very surprising, perhaps even unethical, that the New England Journal of Medicine has published it. It would be more appropriate to publish the data on the website of the pharmaceutical company that has sponsored and written up the study. At least Gilead have been clear that this has not been done in the way that a high quality scientific paper would be written.
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https://www.sciencemediacentre.org/...remdesivir-for-patients-with-severe-covid-19/
 
Yep - that's the long-term recommended methodology for getting drugs approved - and for good reason, Islandboy.

However, in the short term where these drugs are not yet proven through many months (maybe even years) worth of proper double blind clinical trials have been done - and you have a patient currently dying of COVID-19 - do you wait? or do you try it and try to publish it fast enough so that it remains a potential weapon against this bug while it is still ravaging through the population?
 
islandboy said:
My pharmacist friends tell me you cannot be sure a drug is doing what is claimed until proper double blind clinical trials have been done repeatedly by peer evaluation. Simply said: "prove it".

https://www.sciencemediacentre.org/...remdesivir-for-patients-with-severe-covid-19/
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Total agree with what you are saying and that part was in the article I posted.

While Götte said the evidence justifies clinical trials, he cautioned that the results obtained in the lab cannot be used to predict how the drug will work with people.

“We've got to be patient and wait for the results of the randomized clinical trials,” said Götte, whose research was funded by the Canadian Institutes of Health Research, Alberta’s Major Innovation Fund and Gilead Sciences, which manufactures remdesivir.

https://www.folio.ca/u-of-a-virolog...y-enzyme-of-coronavirus-that-causes-covid-19/
 
Interesting, will drones be next?
Fishery Notice - Fisheries and Oceans Canada

Subject: FN0379-Groundfish Trawl - Implementation of Emergency Electronic Monitoring (EM) Pilot Program for At-sea Monitoring in response to COVID-19

On April 2, 2020 the Minister of Fisheries and Oceans Canada issued a Fishery Management Order temporarily suspending the requirement for on board at-sea observers for
45 days to help protect the health of observers and fishers from the spread of COVID-19. On the advice of the Groundfish Trawl Advisory Committee (GTAC) and for the
duration of the Fishery Management Order, DFO is implementing an emergency Electronic Monitoring (EM) pilot program for at-sea monitoring in the groundfish trawl
fishery. These measures are required to ensure continued comprehensive and independent catch monitoring of the groundfish trawl fleet.

Harvesters are hereby notified of the following changes to at-sea monitoring requirements for the groundfish trawl fishery, effective immediately.

All vessels fishing under the groundfish trawl Option A licence conditions shall: be equipped with a functioning electronic monitoring (EM) system from Archipelago
Marine Research, retain all rockfish catch for validation during offload, and hail out as a “Shoreside hake” trip.
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islandboy said:
Doesn't Pres. T claim to be a genius because he had a smart Uncle?
Same claim about inheriting superior knowledge from her parents perhaps?
Ah, to be a teenager again and know everything.
40+ years later I appreciate my father's saying; "The older I get, the more I realize I do not know."
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Quote from Mark Twain, "When I was sixteen I couldn't believe how stupid my father was, but when I reached twenty one I couldn't believe how much he had learned in five years...."
 
New charts for today April 14, 2020

EVmNMuFUEAA243n


EVmP_JCUEAAs7QC
 
agentaqua said:
Yep - that's the long-term recommended methodology for getting drugs approved - and for good reason, Islandboy.

However, in the short term where these drugs are not yet proven through many months (maybe even years) worth of proper double blind clinical trials have been done - and you have a patient currently dying of COVID-19 - do you wait? or do you try it and try to publish it fast enough so that it remains a potential weapon against this bug while it is still ravaging through the population?
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Given I already live with a negative side effect from a drug prescribed years ago, I wait. Lesson learned the hard way.
https://nationalpost.com/news/world...touted-by-trump-stopped-after-11-patients-die
 
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GLG said:
What the hell happened in Calgary!


Got any ideas?
EVmInNjXQAcoXWe
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One of four airports accepting international flights?
 
GLG said:
What the hell happened in Calgary!


Got any ideas?
EVmInNjXQAcoXWe
Click to expand...


That's what happens when you test the population. Compare the % tested vs BC. If you dont test you dont know. It's like driving while staring at the hood ornament.

Nearly 1.5 per cent of Albertans have now been tested for COVID-19 and Alberta maintains the highest per-capita rate of testing among all provinces.

Now compare the number of Calgary or better yet Albertans in hospitals vs BC and you will see a very similar trend.

(Also Calgary has an international airport that accepts international flights.)
Screenshot_20200414-194535_Chrome.jpg EVmP_JCUEAAs7QC.jpeg
 
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IronNoggin said:
Or... as I suggested, it could be an Entitled HoliDazed Fool packing the virus and spreading it on.

Such as:

The mayor of a remote village off British Columbia’s central coast says he’s living proof that someone has ignored the warnings of the province’s health authorities and brought the novel coronavirus to the secluded island.

https://vancouverisland.ctvnews.ca/...rought-covid-19-to-remote-alert-bay-1.4895693

Nog
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Never left the island? Anyone from their community travel for work, shopping or medical care to CR, Nanaimo, or Victoria and return with C-19?
 
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